Nitric oxide and superoxide in biological systems
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چکیده
منابع مشابه
Nitric oxide and superoxide in biological systems
The chemistry of peroxynitrite is complex and highly pHdependent [6,7]. Not only peroxynitrite anion (ONOO-) and its conjugated acid, peroxynitrous acid (ONOOH) (pKa = 6.8) are potent oxidants by themselves [8,9] but also they can lead to the production of secondary reactive species. Moreover, peroxynitrite is capable of nitrating aromatics [10] in a process that can be enhanced by metal centre...
متن کاملNitric oxide and superoxide in biological systems
The measurement of nitric oxide (NO) is important for direct examination of the regulatory roles of this radical in various biological systems. Nitric oxide production indeed participates in the control of major cell functions including reactivity, proliferation and apoptosis. An inappropriate production or metabolism of this radical led to the development of various pathologies, including card...
متن کاملNitric oxide and superoxide in biological systems
DETC: diethyldithiocarbamate, DMPO: 5,5-dimethyl-1-pyrroline N-oxide, DNIC: di-nitrosyl-iron complex, DTCS: N-(dithiocarboxy)sarcosine, EDRF: endothelium-derived relaxing factor, EPR, ESR: electron paramagnetic resonance; electron spin resonance, cGMP: cyclic GMP, Hb: hemoglobin, LPS: lipopolysaccharide, Mb: myoglobin, MGD: N-methyl-D-glucamine dithiocarbamate, MNIC: mono-nitrosyl-iron complex,...
متن کاملNitric oxide and superoxide in biological systems
Oxygen-derived free radicals play a major role in the physiology and pathology of the vessel wall [1]. To assess superoxide anion production (O2) from endothelium, four techniques are mainly used: reduced cytochrome c UV-visible absorption [2,3], ESR spin trapping [4,5], hydroethydine fluorescence [6] and lucigenin-enhanced chemiluminescence [7,8]. The simplest technique which has been used for...
متن کاملWorking with nitric oxide and hydrogen sulfide in biological systems.
Nitric oxide (NO) and hydrogen sulfide (H2S) are gasotransmitter molecules important in numerous physiological and pathological processes. Although these molecules were first known as environmental toxicants, it is now evident that that they are intricately involved in diverse cellular functions with impact on numerous physiological and pathogenic processes. NO and H2S share some common charact...
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ژورنال
عنوان ژورنال: Analusis
سال: 2000
ISSN: 0365-4877,1286-482X
DOI: 10.1051/analusis:2000280443